PIPA527881

ZAK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527881-Each-of-1 In Stock ₹ 47,036.50

PIPA527881 - Each of 1

₹ 47,036.50

In Stock

Quantity

1

Base Price: ₹ 47,036.50

GST (18%): ₹ 8,466.57

Total Price: ₹ 55,503.07

Antigen

ZAK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K20

Gene Alias

AV006891; AZK; B230120H23Rik; HCCS4; HCCS-4; Human cervical cancer suppressor gene 4 protein; leucine zipper- and sterile alpha motif kinase ZAK; Leucine zipper- and sterile alpha motif-containing kinase; Map3k20; Mitogen-activated protein kinase kinase kinase 20; Mitogen-activated protein kinase kinase kinase MLT; mixed lineage kinase 7; mixed lineage kinase with a leucine zipper and a sterile alpha motif; mixed lineage kinase-related kinase; mixed lineage kinase-related kinase MRK-beta; MLK7; mLklak; MLK-like mitogen-activated protein triple kinase; MLK-related kinase; MLT; MLTK; MLTKalpha; MLTKbeta; MRK; pk; RGD1561394; SFMMP; sterile alpha motif and leucine zipper containing kinase AZK; sterile alpha motif- and leucine zipper-containing kinase AZK; sterile-alpha motif and leucine zipper containing kinase AZK; ZAK

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51776

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.92 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9NYL2

Gene Symbols

MAP3K20

Immunogen

Recombinant fragment corresponding to a region within amino acids 306 and 609 of Human ZAK

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A549
  • Predicted reactivity: Mouse (93%), Bovine (93%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ZAK is a leucine zipper-containing mitogen-activated protein related to the MLKs in both sequence and function
  • Like the MLKs and other MAP3Ks, ZAK activates MAP2Ks
  • ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif
  • This magnesium-binding protein forms homodimers and is located in the cytoplasm
  • The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells
  • The protein also has pro-apoptotic activity
  • Alternate transcriptional splice variants, encoding different isoforms, have been characterized.