PIPA527981

GSTM5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527981-Each-of-1 In Stock ₹ 47,392.50

PIPA527981 - Each of 1

₹ 47,392.50

In Stock

Quantity

1

Base Price: ₹ 47,392.50

GST (18%): ₹ 8,530.65

Total Price: ₹ 55,923.15

Antigen

GSTM5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSTM5

Gene Alias

fibrous sheath component 2; Fsc2; glutathione S-alkyltransferase M5; glutathione S-aralkyltransferase M5; glutathione S-aryltransferase M5; glutathione S-transferase M5; glutathione S-transferase Mu 5; glutathione S-transferase, mu 5; glutathione-S-transferase, mu 5; GST class-mu 5; Gstm3; GSTM5; GSTM5-5; GTM5; S-(hydroxyalkyl)glutathione lyase M5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14866, 2949

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P46439, P48774

Gene Symbols

GSTM5

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 218 of Human GSTM5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: mouse brain
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families
  • At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta
  • This gene encodes a glutathione S-transferase that belongs to the mu class
  • The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione
  • The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic
  • These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs
  • Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.