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PIPA528265

ZMYM2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528265-Each-of-1 In Stock ₹ 47,392.50

PIPA528265 - Each of 1

₹ 47,392.50

In Stock

Quantity

1

Base Price: ₹ 47,392.50

GST (18%): ₹ 8,530.65

Total Price: ₹ 55,923.15

Antigen

ZMYM2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ZMYM2

Gene Alias

5830413P05Rik; FIM; Fused in myeloproliferative disorders protein; MYM; RAMP; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; RP11-264J4.7; SCLL; Zfp198; zinc finger MYM-type containing 2; zinc finger MYM-type protein 2; Zinc finger protein 198; zinc finger, MYM-type 2; Zmym2; ZNF198

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

76007, 7750

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.57 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9CU65, Q9UBW7

Gene Symbols

ZMYM2

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 856 and 1336 of Human ZNF198

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: human ESC
  • Predicted reactivity: Mouse (95%), Rhesus Monkey (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown
  • It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain
  • Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein
  • This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5
  • This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.