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PIPA528272

CSNK1A1L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528272-Each-of-1 In Stock ₹ 46,502.50

PIPA528272 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CSNK1A1L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CSNK1A1L

Gene Alias

casein kinase 1 alpha 1 like; casein kinase 1, alpha 1-like; casein kinase I alpha S-like; casein kinase I isoform alpha-like; CK1; CKI-alpha-like; CSNK1A1L

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

122011

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.53 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q8N752

Gene Symbols

CSNK1A1L

Immunogen

Recombinant fragment corresponding to a region within amino acids 10 and 228 of Human Casein Kinase 1 alpha 1L

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Recommended positive controls: A549, rat thymus
  • Predicted reactivity: Rhesus Monkey (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • CSNK1A1L serine/threonine kinase or CK1-alpha dynamically associates with the CBM complex upon T cell receptor engagement to participate in cytokine production and lymphocyte proliferation which has a contrasting role by subsequently promoting the phosphorylation and inactivation of CARMA1
  • It governs antigen-receptor-induced NF-kappa-B activation and human lymphoma cell survival
  • These kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates
  • It can phosphorylate a large number of proteins including CTNNB1, PER1, and PER2
  • CSNK1A1 also participates in Wnt signaling
  • It may play a role in segregating chromosomes during mitosis, as well as, cytoskeleton diassembly which may regulate epithelial cell migration.