WNK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528382-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA528382 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
WNK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
WNK1
Gene Alias
6430573H23Rik; EG406236; Erythrocyte 65 kDa protein; HSAN2; HSN2; hWNK1; KDP; KIAA0344; Kinase deficient protein; MGC163339; MGC163341; mKIAA0344; p65; PPP1R167; Prkwnk1; prostate-derived sterile 20-like kinase; protein kinase lysine-deficient 1; Protein kinase with no lysine 1; protein phosphatase 1, regulatory subunit 167; PSK; Serine/threonine-protein kinase WNK1; serine/threonine-protein kinase WNK1 1; serine/threonine-protein kinase WNK1 2; With no K; WNK lysine deficient protein kinase 1; WNK lysine deficient protein kinase 1 isoform; WNK1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
232341, 65125
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.18 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
P83741, Q9H4A3
Gene Symbols
WNK1
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1079 and 1293 of Human WNK1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A431, H1299, HeLa, HepG2
- Predicted reactivity: Mouse (92%), Rat (93%), Chimpanzee (98%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- WNK1 serine/threonine kinase is a member of the WNK subfamily
- WNK1 may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions
- Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II
- WNK plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation
- Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively
- Activates SCNN1A, SCNN1B, SCNN1D, and SGK1
- WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron
- Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.