SERTAD1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528460-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA528460 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
SERTAD1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SERTAD1
Gene Alias
1110032C13Rik; AV000455; AW456625; CDK4-binding protein p34SEI; CDK4-binding protein p34SEI1; p34SEI-1; PHD zinc finger- and bromodomain-interacting protein 1; SEI1; SEI-1; SERTA domain containing 1; SERTA domain-containing protein 1; SERTAD1; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIPBR1; TRIP-Br1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29950
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9UHV2
Gene Symbols
SERTAD1
Immunogen
Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human SERTAD1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Molt-4
- Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SEI-1, also known as SERTAD1 (SERTA domain containing 1) or TRIP-Br1 (Transcriptional regulator interacting with the PHD-bromodomain 1), is a transcriptional regulator that integrates signals provided by transcription factors
- Acting at E2F-responsive promoters, SEI-1 interacts with the PHD- and bromodomains of proteins such as TIF1 and DP-1, thereby transmitting their signals to the promoter and stimulating transcriptional activity
- SEI-1 exists as a multiprotein complex with E2F-1 and DP-1 and is expressed at different levels throughout the cell cycle, allowing it to regulate cell cycle progression via promoter control during the G1 and S phases
- Additionally, SEI-1 can render the activity of the cyclin D-Cdk4 complex, an important catalyst of the cell cycle, resistant to the inhibitory effects of p16
- Overexpression of SEI-1 is implicated in the development of squamous cell carcinomas of the head and neck.