WHIP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528532-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA528532 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
WHIP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
WRNIP1
Gene Alias
4833444L21Rik; ATPase WRNIP1; bA420G6.2; FLJ22526; putative helicase RUVBL; RP11-420G6.2; UniProtKB:Q96S55}; Werner helicasae interacting protein 1; Werner helicase interacting protein 1; Werner helicase-interacting protein 1; Werner syndrome homolog interacting protein; Whip; Wrnip; Wrnip1; wrnip1 {ECO:0000250
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56897
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.69 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q96S55
Gene Symbols
WRNIP1
Immunogen
Recombinant fragment corresponding to a region within amino acids 403 and 665 of Human WHIP
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (80%), Xenopus laevis (82%), Bovine (90%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN)
- The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein
- This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus
- It has sequence similarity to replication factor C family proteins and is conserved from E
- coli to human
- This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis
- This protein also interacts with nucleoporins at nuclear pore complexes
- Two transcript variants encoding different isoforms have been isolated for this gene.