Doublecortin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528536-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA528536 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
Doublecortin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DCX
Gene Alias
DBCN; Dbct; DC; Dcn; DCX; doublecortex; doublecortin; doublin; lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1641
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.76 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O43602
Gene Symbols
DCX
Immunogen
Recombinant fragment corresponding to a region within amino acids 154 and 441 of Human Doublecortin
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Raji, human DCX-transfected 293T
- Predicted reactivity: Mouse (99%), Rat (97%), Chicken (94%), Bovine (96%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation
- DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules
- It contains two doublecortin domains, which bind microtubules
- In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex
- Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.