STUB1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529024-Each-of-1 | In Stock | ₹ 51,620.00 |
PIPA529024 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,620.00
GST (18%): ₹ 9,291.60
Total Price: ₹ 60,911.60
Antigen
STUB1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STUB1
Gene Alias
0610033N24Rik; 2210017D18Rik; 2310040B03Rik; Antigen NY-CO-7; AW046544; Carboxy terminus of Hsp70-interacting protein; CHIP; CLL-associated antigen KW-8; E3 ubiquitin-protein ligase CHIP; heat shock protein A binding protein 2 (c-terminal); HSPABP2; LA16c-313D11.6; NY-CO-7; PP1131; RING-type E3 ubiquitin transferase CHIP; SCAR16; SDCCAG7; serologically defined colon cancer antigen 7; STIP1 homology and U box-containing protein 1; STIP1 homology and U-box containing protein 1; STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase; Stub1; UBOX1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10273, 56424
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.74 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9UNE7, Q9WUD1
Gene Symbols
STUB1
Immunogen
Synthetic peptide corresponding to a region within amino acids 168 and 262 of Human STUB1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2
- Predicted reactivity: Mouse (100%), Rat (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- A recently identified protein, termed carboxyl terminus of hsc70-interacting protein (CHIP), has been shown to interact both with the constitutive form of hsc70 and the stress inducible form, hsp70
- This novel 35 kDa cytoplasmic protein has been shown to be highly expressed in striated muscle in vivo
- Additional studies have shown that this protein is expressed over a broad range of cultured tissues
- Through immunoprecipitation experiments, CHIP has been shown to directly bind to the carboxyl terminus of hsc70 and hsp70 where it decreases ATPase activity and reduces overall chaperone efficiency
- CHIP has also been identified as an important protein in the ubiquitin-proteasome system
- CHIP contains a U-box domain and acts as an E3 ubiquitin-ligase in conjunction with hsc70 and hsp90.