TDG Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529140-Each-of-1 | In Stock | ₹ 52,599.00 |
PIPA529140 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,599.00
GST (18%): ₹ 9,467.82
Total Price: ₹ 62,066.82
Antigen
TDG
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TDG
Gene Alias
C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6996
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q13569
Gene Symbols
TDG
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 410 of Human TDG
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLa, Jurkat, Raji, NCI-H929, TDG-transfected 293T
- Predicted reactivity: Human (99%), Mouse (88%), Rat (87%), Bovine (91%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family
- Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mis paired thymine
- With lower activity, this enzyme also removes thymine from C/T and T/T mispairings
- TDG can also remove uracil and 5-bromouracil from mispairings with guanine
- This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine
- This gene may have a pseudogene in the p arm of chromosome 12.