NALP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529196-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA529196 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
NALP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLRP2
Gene Alias
CLR19.9; E330007A02Rik; FLJ20510; LOC684545; NACHT, leucine rich repeat and PYD containing 2; NACHT, LRR and PYD containing protein 2; NACHT, LRR and PYD domains-containing protein 2; NALP2; NBS1; NLR family pyrin domain containing 2; NLR family, pyrin domain containing 2; NLRP2; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2; nucleotide-binding site protein 1; PAN1; PYPAF2; PYRIN domain and NACHT domain-containing protein 1; PYRIN-containing APAF1-like protein 2; similar to NACHT, leucine rich repeat and PYD containing 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55655
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9NX02
Gene Symbols
NLRP2
Immunogen
Recombinant fragment corresponding to a region within amino acids 506 and 736 of Human NALP2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A431, H1299, HeLa, Molt-4
- Predicted reactivity: Rhesus Monkey (82%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli
- Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD)
- This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1-b-processing activity and is thought to function as a modulator of NF-kappa-B and procaspase-1 activation in macrophages
- It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs)
- At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.