PIPA529326

HK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529326-Each-of-1 In Stock ₹ 52,421.00

PIPA529326 - Each of 1

₹ 52,421.00

In Stock

Quantity

1

Base Price: ₹ 52,421.00

GST (18%): ₹ 9,435.78

Total Price: ₹ 61,856.78

Antigen

HK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Hk2

Gene Alias

AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100009677, 15277, 25059, 3099

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.76 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

A2PYL6, O08528, P27881, P52789

Gene Symbols

Hk2

Immunogen

Recombinant fragment corresponding to a region within amino acids 53 and 342 of Human Hexokinase II

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Equine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, Mouse brain
  • Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (86%), Pig (96%), Chicken (88%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV
  • Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway
  • Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P
  • Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle
  • Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.