PHKG2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529332-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA529332 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PHKG2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PHKG2
Gene Alias
1500017I02Rik; GSD9C; MGC129049 protein; phkg2; PHK-gamma-LT; PHK-gamma-T; Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; phosphorylase b kinase gamma catalytic chain, testis/liver isoform; phosphorylase kinase; phosphorylase kinase catalytic subunit gamma 2; phosphorylase kinase gamma subunit 2; phosphorylase kinase subunit gamma 2; phosphorylase kinase subunit gamma-2; phosphorylase kinase, gamma 2 (testis); Phosphorylase kinase, gamma 2 (testis/liver); PSK-C3; serine/threonine-protein kinase PHKG2; similar to phosphorylase kinase, gamma 2 (testis); zgc:55863; zgc:55863 protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5261
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.24 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P15735
Gene Symbols
PHKG2
Immunogen
Recombinant fragment corresponding to a region within amino acids 114 and 406 of Human PHKG2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLa
- Predicted reactivity: Mouse (92%), Rat (92%), Pig (93%), Sheep (94%), Bovine (94%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- PHKG2 is a testis/liver isoform of the phosphorylase kinase gamma subunit
- Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta
- The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes
- The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene
- The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by PHKG2
- The delta subunit is a calmodulin and can be encoded by three different genes
- The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation
- The delta subunit mediates the dependence of the enzyme on calcium concentration
- Mutations in PHKG2 cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis
- Alternatively spliced transcript variants encoding different isoforms have been identified in PHKG2.