TRIB1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529407-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA529407 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TRIB1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRIB1
Gene Alias
A530090O15Rik; C8FW; Gig2; GIG-2; G-protein-coupled receptor induced protein; G-protein-coupled receptor induced protein GIG2; G-protein-coupled receptor-induced gene 2 protein; G-protein-coupled receptor-induced protein 2; phosphoprotein regulated by mitogenic pathways; SKIP1; Trb1; TRB-1; Trib1; tribbles homolog 1; tribbles homolog 1 (Drosophila); tribbles pseudokinase 1; tribbles-like protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10221
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q96RU8
Gene Symbols
TRIB1
Immunogen
Recombinant fragment corresponding to a region within amino acids 104 and 372 of Human TRIB1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A431, HeLa
- Predicted reactivity: Mouse (97%), Rat (96%), Xenopus laevis (81%), Dog (97%), Rhesus Monkey (99%), Bovine (98%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- TRIB1 also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities
- Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity
- Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation
- ERK activation was enhanced by TRIB1
- Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1
- Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.