Creatine Kinase MT Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529471-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA529471 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Creatine Kinase MT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CKMT1A
Gene Alias
acidic-type mitochondrial creatine kinase; CKMT; CKMT1; CKMT1A; CKMT1B; Creatine kinase U-type, mitochondrial; creatine kinase, mitochondrial 1 (ubiquitous); creatine kinase, mitochondrial 1, ubiquitous; creatine kinase, mitochondrial 1A; creatine kinase, mitochondrial 1B; mia-CK; mi-CK; Mt-CK; ScCKmit; UbCKmit; ubiquitous mitochondrial creatine kinase; UMTCK; U-MtCK
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1159, 548596
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.0 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P12532
Gene Symbols
CKMT1A, CKMT1B
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 5 and 262 of Human Creatine kinase MT
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, H1299, HeLa
- Predicted reactivity: Chicken (91%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine
- It belongs to the creatine kinase isoenzyme family
- It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes
- Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes
- Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis
- Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase
- Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.