PIPA529495

ATP Citrate Lyase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529495-Each-of-1 In Stock ₹ 52,421.00

PIPA529495 - Each of 1

₹ 52,421.00

In Stock

Quantity

1

Base Price: ₹ 52,421.00

GST (18%): ₹ 9,435.78

Total Price: ₹ 61,856.78

Antigen

ATP Citrate Lyase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Acly

Gene Alias

17-beta-HSD 10; 17-beta-hydroxysteroid dehydrogenase 10; 17bHSD10; 17b-HSD10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3-hydroxyacyl-CoA dehydrogenase type-2; A730098H14Rik; ABAD; AB-binding alcohol dehydrogenase; ACL; ACLY; Ads9; amyloid beta-peptide binding protein; amyloid-beta peptide binding alcohol dehydrogenase; ATP citrate lyase; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; ATPCL; AW538652; CAMR; citrate cleavage enzyme; CLATP; DUPXp11.22; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; ERAB; HADH2; HCD2; Hsd17b10; hydroxyacyl-Coenzyme A dehydrogenase type II; hydroxyacyl-Coenzyme A dehydrogenase, type II; hydroxysteroid (17-beta) dehydrogenase 10; hydroxysteroid 17-beta dehydrogenase 10; hydroxysteroid dehydrogenase 10; MHBD; Mitochondrial ribonuclease P protein 2; mitochondrial RNase P protein 2; mitochondrial RNase P subunit 2; MRPP2; MRX17; MRX31; MRXS10; SCHAD; SDR5C1; short chain dehydrogenase/reductase family 5C member 1; short chain dehydrogenase/reductase family 5C, member 1; short chain L-3-hydroxyacyl-CoA dehydrogenase; short chain L-3-hydroxyacyl-CoA dehydrogenase type 2; short chain type dehydrogenase/reductase XH98G2; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; XH98G2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

104112, 24159, 47

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P16638, P53396, Q91V92

Gene Symbols

Acly

Immunogen

Recombinant fragment corresponding to a region within amino acids 743 and 1038 of Human ATP citrate lyase

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLa, Raji, mouse brain, PC-12, Rat-2
  • Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (91%), Pig (98%), Chicken (95%), Sheep (99%), Bovine (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues
  • The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits
  • It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate
  • The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis
  • In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine
  • Two transcript variants encoding distinct isoforms have been identified for this gene.