Calpain 3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529721-Each-of-1 | In Stock | ₹ 49,172.50 |
PIPA529721 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,172.50
GST (18%): ₹ 8,851.05
Total Price: ₹ 58,023.55
Antigen
Calpain 3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Capn3
Gene Alias
AI323605; calcium-activated neutral proteinase 3; calpain 3; calpain 3, (p94); calpain L3; Calpain p94; calpain p94, large [catalytic] subunit; calpain, large polypeptide L3; calpain-3; CANP 3; CANP3; CANPL3; Capa3; Capa-3; CAPN 3; CAPN3; LGMD 2A; LGMD2; LGMD2A; Lp82; Lp84; Lp85; MGC10767; MGC11121; MGC14344; MGC4403; Muscle-specific calcium-activated neutral protease 3; muscle-specific calcium-activated neutral protease 3 large subunit; NCL1; nCL-1; New calpain 1; p94; skeletal muscle specific calpain p94
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
825
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.43 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P20807
Gene Symbols
Capn3
Immunogen
Recombinant fragment corresponding to a region within amino acids 528 and 741 of Human Calpain 3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: H1299, HeLa, HepG2, Molt-4
- Predicted reactivity: Mouse (86%), Rat (89%), Pig (88%), Sheep (87%), Bovine (88%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Calpain, an intracellular calcium-dependent protease that cleaves cytoskeletal and submembranous proteins, plays a role in cytoskeletal reorganization and muscle protein degradation
- Calpain is a heterodimer composed of a small regulatory subunit and one of three large catalytic subunits, designated calpain 1, calpain 2 and calpain 3
- Calpain 3 (calpain p94) is a muscle-preferred calcium activated neutral protease that localizes to the nucleus
- Mutations involving the calpain 3 gene are associated with limb-girdle muscle dystrophy type 2A, a form of autosomal recessive and progressive neuromuscular diso4
- Calpastatin regulates calpain by inhibiting both the proteolytic activity of calpain and its binding to membranes
- Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing.