PIPA529731
Emerin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529731-Each-of-1 | In Stock | ₹ 48,015.50 |
PIPA529731 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,015.50
GST (18%): ₹ 8,642.79
Total Price: ₹ 56,658.29
Antigen
Emerin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Emd
Gene Alias
AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2010
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P50402
Gene Symbols
Emd
Immunogen
Recombinant fragment corresponding to a region within amino acids 48 and 254 of Human Emerin
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLa nucleus
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight
- The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar μgtraviolet (UV)-induced DNA damages
- Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA
- The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region
- A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity
- A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity
- Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.