PIPA529788

Caspase 4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529788-Each-of-1 In Stock ₹ 53,400.00

PIPA529788 - Each of 1

₹ 53,400.00

In Stock

Quantity

1

Base Price: ₹ 53,400.00

GST (18%): ₹ 9,612.00

Total Price: ₹ 63,012.00

Antigen

Caspase 4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CASP4

Gene Alias

apoptotic cysteine protease Mih1/TX; Casp11; CASP-11; CASP4; CASP-4; caspase 11; caspase 4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; Caspase-11; Caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-4 subunit p20; Caspl; ICE and Ced-3 homolog 2; ICE(rel)II; ICE(rel)-II; ICEREL-II; ICH2; ICH-2; Ich3; ich-3; Mih1; Mih1/TX; protease ICH-2; Protease ICH-3; Protease TX; TX

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

837

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.89 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P49662

Gene Symbols

CASP4

Immunogen

Recombinant fragment corresponding to a region within amino acids 148 and 360 of Human Caspase 4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: H1299, K562, THP-1, HL-60, myc-tagged human caspas4-transfected 293T cells
  • Predicted reactivity: Rhesus Monkey (96%), Bovine (84%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family
  • Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
  • Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit
  • Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits
  • This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor
  • When overexpressed, this gene induces cell apoptosis
  • Alternative splicing results in transcript variants encoding distinct isoforms.