BACE2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529882-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA529882 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
BACE2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BACE2
Gene Alias
1110059C24Rik; 56 kDa aspartic-like protease; AEPLC; AI850424; ALP56; ARP1; asp 1; ASP1; ASP21; Aspartic-like protease 56 kDa; Aspartyl protease 1; Bace2; BAE2; be; beta secretase 2; Beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; beta-site APP-cleaving enzyme 2; CDA13; CEAP1; Down region aspartic protease; Down syndrome region aspartic protease; DRAP; memapsin 1; memapsin-1; Membrane-associated aspartic protease 1; theta-secretase; transmembrane aspartic proteinase Asp1; UNQ418/PRO852
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25825, 288227
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.83 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q6IE75, Q9Y5Z0
Gene Symbols
BACE2
Immunogen
Recombinant fragment corresponding to a region within amino acids 319 and 518 of Human BACE2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Mouse (88%), Rat (88%), Bovine (90%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP)
- BACE2 cleaves APP between residues 690 and 691
- This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP
- BACE2 is also know to cleave APP between residues 671 and 672
- Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.