PIPA529886

CD177 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529886-Each-of-1 In Stock ₹ 46,502.50

PIPA529886 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CD177

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD177

Gene Alias

1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57126

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q8N6Q3

Gene Symbols

CD177

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 166 and 385 of Human CD177

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
  • Predicted reactivity: Human (99%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils
  • Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application
  • Ligand of CD177 has been identified as CD31 (PECAM-1)
  • CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule
  • The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).