COMT Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529901-Each-of-1 | In Stock | ₹ 47,392.50 |
PIPA529901 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,392.50
GST (18%): ₹ 8,530.65
Total Price: ₹ 55,923.15
Antigen
COMT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Comt
Gene Alias
Catechol O-methyltransferase; catecholamine-O-methyltransferase; catechol-O-methyltransferase; catechol-O-methyltransferase 1; catechol-O-methyltransferase isoform; Comt; Comt1; D16Wsu103e; D330014B15Rik; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; OTTHUMP00000197749; OTTHUMP00000197750; testicular tissue protein Li 42
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1312, 24267
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.52 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P21964, P22734
Gene Symbols
Comt
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 149 of Human COMT
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: K562
- Predicted reactivity: Human (99%), Mouse (83%), Rat (81%), Dog (81%), Pig (85%), Rhesus Monkey (94%), Bovine (83%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine
- This O-methylation results in one of the major degradative pathways of the catecholamine transmitters
- In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease
- COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT)
- The differences between S-COMT and MB-COMT reside within the N-termini
- Several transcript variants are formed through the use of alternative translation initiation sites and promoters.