NPTX2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530105-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA530105 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NPTX2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NPTX2
Gene Alias
apexin; Narp; neuro activity regulated petaxin; neuronal activity-regulated pentaxin; neuronal activity-regulated pentraxin; neuronal pentraxin 2; neuronal pentraxin II; Neuronal pentraxin-2; NP2; NP-II; Nptx2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4885
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.25 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P47972
Gene Symbols
NPTX2
Immunogen
Recombinant fragment corresponding to a region within amino acids 187 and 431 of Human NP2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Jurkat
- Predicted reactivity: Mouse (98%), Rat (98%), Guinea pig (95%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1
- Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain
- NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity
- NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis
- Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson’s disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD.