MRPL12 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530159-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA530159 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MRPL12
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MRPL12
Gene Alias
0610034O11Rik; 1500031N16Rik; 39S ribosomal protein L12, mitochondrial; 5c5-2; FLJ60124; hypothetical protein LOC550391; im:6893415; L12mt; MGC8610; Mitochondrial large ribosomal subunit protein bL12m; mitochondrial ribosomal protein L12; mitochondrial ribosomal protein L7/12; MRPL12; MRP-L12; MRP-L31/34; MRPL7; MRPL7/L12; ribosomal protein, mitochondrial, L12; Rpm12; RPML12; zgc:112445
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56282, 6182
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.56 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P52815, Q9DB15
Gene Symbols
MRPL12
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 198 of Human MRPL12
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A431, H1299, HeLa, HepG2, mouse brain
- Predicted reactivity: Mouse (84%), Rat (82%), Rhesus Monkey (94%), Bovine (86%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein that is involved in protein synthesis within the mitochondrion
- MRPL12 is enhanced in growth-stimulated cells as a result of transcriptional activation, suggesting that it may function as a translational regulator of mitochondrial mRNAs
- Impairment of MRPL12 leads to reduction in cell growth rate, decreased mitochondrial ATP production and abolition of mitochondrial oxidative phosphorylation
- MRPL12 is cleaved during its translocation across the mitochondrial membrane and it exists as dimers that bind the large ribosomal subunit
- MRPL12 is 198 amino acids in length, belongs to the ribosomal protein L12P family and is highly expressed in the colon.