IRF9 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530378-Each-of-1 | In Stock | ₹ 49,706.50 |
PIPA530378 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,706.50
GST (18%): ₹ 8,947.17
Total Price: ₹ 58,653.67
Antigen
IRF9
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRF9
Gene Alias
gamma 48kDa; IFN alpha responsive transcription factor subunit; IFN-alpha-responsive transcription factor subunit; interferon dependent positive acting transcription factor 3 gamma; interferon regulatory factor 9; Interferon-stimulated gene factor 3 gamma; interferon-stimulated transcription factor 3; interferon-stimulated transcription factor 3, gamma (48kD); interferon-stimulated transcription factor 3, gamma 48kDa; IRF9; Irf-9; ISGF3; ISGF-3 gamma; ISGF3 p48 subunit; ISGF3G; p48; transcriptional regulator ISGF3 subunit gamma; Unknown (protein for MGC:126912); Unknown (protein for MGC:92097); zgc:92097
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10379
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.63 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q00978
Gene Symbols
IRF9
Immunogen
Recombinant fragment corresponding to a region within amino acids 171 and 393 of Human IRF9
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (81%), Pig (87%), Rhesus Monkey (96%), Bovine (84%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Transcription factor that plays an essential role in anti-viral immunity
- It mediates signaling by type I IFNs (IFN-alpha and IFN-beta)
- Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2
- IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus
- ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state
- [UniProt]