RBM4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA531887-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA531887 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
RBM4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RBM4
Gene Alias
4921506I22Rik; hLark; LARK; lark homolog; Lark1; Mlark; RBM4; RBM4A; RNA binding motif protein 4; rna-binding; RNA-binding motif protein 4; RNA-binding motif protein 4a; RNA-binding protein 4; transcriptional coactivator CoAZ; Unknown (protein for MGC:128953); ZCCHC21; ZCRB3A; zinc finger CCHC-type and RNA binding motif 3A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19653, 5936
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q8C7Q4, Q9BWF3
Gene Symbols
RBM4
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 206 of Human RBM4
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLa, Neuro2A, GL261, C8D30
- Predicted reactivity: Mouse (98%), Rat (98%), Pig (98%), Chimpanzee (100%), Bovine (98%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation
- Modulates alternative 5'-splice site and exon selection
- Acts as a muscle cell differentiation-promoting factor
- Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation
- Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin
- Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs
- Required for the translational activation of PER1 mRNA in response to circadian clock
- Binds directly to the 3'-UTR of the PER1 mRNA
- Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation
- Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress
- Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions
- Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs
- Associates with miRNAs during muscle cell differentiation
- Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro
- [UniProt]