POLR3E Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA531931-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA531931 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
POLR3E
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POLR3E
Gene Alias
DNA-directed RNA polymerase III 80 kDa polypeptide; DNA-directed RNA polymerase III subunit RPC5; KIAA1452; POLR3E; polymerase (RNA) III (DNA directed) polypeptide E; polymerase (RNA) III (DNA directed) polypeptide E (80kD); polymerase (RNA) III subunit E; RGD1308086; RNA polymerase III 80 kDa subunit RPC5; RNA polymerase III polypeptide E; RNA polymerase III subunit 5; RNA polymerase III subunit C5; RNA polymerase III subunit E; RPC5; Sex-lethal interactor homolog; Sin; Sxl interactor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55718
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9NVU0
Gene Symbols
POLR3E
Immunogen
Recombinant fragment corresponding to a region within amino acids 89 and 323 of Human POLR3E
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Jurakt
- Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (82%), Xenopus laevis (80%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
- Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs
- Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters
- Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses
- Acts as nuclear and cytosolic DNA sensor involved in innate immune response
- Can sense non-self dsDNA that serves as template for transcription into dsRNA
- The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.