PIPA532165

KIFC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532165-Each-of-1 In Stock ₹ 46,502.50

PIPA532165 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

KIFC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Kifc2

Gene Alias

KIFC2; kinesin family member C2; kinesin-like protein KIFC2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16581, 90990

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O08672, Q96AC6

Gene Symbols

Kifc2

Immunogen

Recombinant fragment corresponding to a region within amino acids 301 and 566 of Human KIFC2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: K562, THP-1
  • Predicted reactivity: Mouse (85%), Rat (84%), Bovine (87%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division
  • Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation
  • These proteins have a modular structure which includes a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis
  • In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain
  • An expansive phylogenetic tree of kinesins and kinesin-related proteins (KRPs) has been assembled based on this information
  • Kinesin C2 (KIFC2) is a C-type kinesin based on the position of the motor domain towards the carboxyl-terminus of the protein and is similar to members of the karyogamy protein 3 (KAR3) family involved in cell division
  • KIFC2 protein expression has been demonstrated in axons and dendrites of the central and peripheral nervous system
  • Unlike other C-type motor proteins, KIFC2 appears to play a role in retrograde axonal transport.