IGF2BP3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA532470-Each-of-1 | In Stock | ₹ 45,390.00 |
PIPA532470 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,390.00
GST (18%): ₹ 8,170.20
Total Price: ₹ 53,560.20
Antigen
IGF2BP3
Classification
Polyclonal
Gene
IGF2BP3
Gene Alias
CT98, IMP-3, IMP3, KOC1, VICKZ3, IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, VICKZ family member 3, cancer/testis antigen 98, hKOC, insulin-l
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10643
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Gene Accession No.
O00425
Gene Symbols
IGF2BP3
Immunogen
Synthetic peptide corresponding to internal region of human KOC/L523S.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
- A suggested positive control is prostate carcinoma or placenta tissue
- Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some maligcies
- IMP-3 is expressed in maligt melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas
- IMP-3 appears to be involved in the progression of maligt melanoma and may play an important role in the regulation of the biologic behavior of this tumor.