PIPA532657

ADAMTS4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532657-Each-of-1 In Stock ₹ 46,502.50

PIPA532657 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ADAMTS4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ADAMTS4

Gene Alias

3830423K05; a disintegrin and metallopeptidase with thrombospondin motifs 4; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 4; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 4; ADAM metallopeptidase with thrombospondin type 1 motif, 4; ADAMs; ADAM-TS 4; ADAMTS family member; ADAMTS-2; Adamts4; ADAM-TS4; ADAMTS-4; ADMP-1; Aggrecanase; Aggrecanase 1; aggrecanase-1; disintegrin and metalloproteinase with thrombospondin motifs 2; KIAA0688; metalloendopeptidases; metalloproteinase; mKIAA0688; UNQ769/PRO1563

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100033914, 100157276, 240913, 488651, 66015, 9507

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

O75173, Q8BNJ2, Q9ESP7

Gene Symbols

ADAMTS4

Immunogen

Synthetic 16 amino acid peptide from internal region of human ADAMTS4.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Canine, Equine, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Elephant, Panda, Horse, Pig, Opossum (100%); Guinea pig (94%)
  • For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer
  • After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
  • This gene encodes a member of the ADAMTS protein family
  • Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif
  • Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains
  • The enzyme encoded by this gene lacks a C-terminal TS motif
  • It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein
  • The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.