HTR2A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA532865-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA532865 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
HTR2A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Htr2a
Gene Alias
5-HT-2; 5Ht-2; 5-HT2 receptor; 5-HT2A; 5-HT-2A; 5HT2A Receptor; 5-HT2A receptor; 5-HT2A/2C; 5-HT2A/2C receptor; 5-hydroxytryptamine (serotonin) receptor 2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5-hydroxytryptamine 2 receptor; 5-hydroxytryptamine receptor 2A; E030013E04; Htr2; Htr-2; HTR2A; serotonin 5HT-2 receptor; serotonin 5-HT-2A receptor; serotonin receptor 2A; SR2A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100009685, 3356, 397432
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P28223, P50129
Gene Symbols
Htr2a
Immunogen
Synthetic 17 amino acid peptide from N-Terminus of human 5HT2A Receptor.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Equine, Human, Porcine
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Panda, Horse, Pig, Bat, Elephant (100%); Marmoset, Bovine, Dog (94%); Hamster (82%)
- Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K
- In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively
- Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors
- The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin
- SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia
- SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders
- SR-2C is thought to mediate the effects of atypical antipsychotic drugs.