NKCC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533024-Each-of-1 | In Stock | ₹ 47,481.50 |
PIPA533024 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
NKCC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SLC12A2
Gene Alias
9330166H04Rik; basolateral NaK(2Cl) cotransporter; basolateral Na-K-Cl symporter; BSC; BSC2; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; little ears; lte; mBSC2; Na-K-2Cl- cotransporter; Na-K-Cl cotransporter; NKCC1; PPP1R141; protein phosphatase 1, regulatory subunit 141; Slc12a2; slc12a4; sodium/potassium/chloride cotransporters; sodium/potassium/chloride transporters; solute carrier family 12 (potassium/chloride transporters), member 2; solute carrier family 12 (potassium/chloride transporters), member 4; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; solute carrier family 12 member 2; solute carrier family 12, member 2; sy-ns; zfnkcc1; zgc:85961; zmp:0000000537
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6558
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P55011
Gene Symbols
SLC12A2
Immunogen
Synthetic 18 amino acid peptide from internal region of human SLC12A2 / NKCC1.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Bovine, Pig (89%) Ferret, Dog, Bat, Panda (83%)
- NKCC1 mediates sodium and chloride transport and reabsorption
- NKCC1 is a membrane protein and is important in maintaining proper ionic balance and cell volume
- NKCC1 is an electrically silent transporter system that mediates sodium and chloride reabsorption
- Further, NKCC1 plays a vital role in the regulation of ionic balance and cell volume and is phosphorylated in response to DNA damage
- Three transcript variants encoding two different isoforms have been found for NKCC1
- Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.