TAOK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533073-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA533073 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TAOK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TAOK1
Gene Alias
2810468K05Rik; AU020252; D130018F14Rik; FLJ14314; h hTAOK1; H KIAA1361; hKFC-B; hTAOK1; KFC-B; Kiaa1361; Kinase from chicken homolog B; MAP3K16; MARK Kinase; Markk; microtubule affinity regulating kinase kinase; mKIAA1361; prostate-derived STE20-like kinase 2; prostate-derived sterile 20-like kinase 2; PSK2; PSK-2; serine/threonine protein kinase TAO1; serine/threonine protein kinase TAO1 homolog; serine/threonine-protein kinase TAO1; STE20-like kinase PSK2; tao; TAO kinase 1; TAO1; TAOK1; Thousand and one amino acid protein 1; thousand and one amino acid protein kinase 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100059705, 100342573, 100622172, 100758772, 216965, 286993, 480632, 57551
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
O88664, Q5F2E8, Q7L7X3
Gene Symbols
TAOK1
Immunogen
Synthetic 17 amino acid peptide from C-Terminus of human TAOK1.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat, X. laevis
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Xenopus (100%); Zebrafish (88%)
- Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K
- TAOK1 is a serine/threonine-protein kinase involved in regulation of the p38-containing stress-responsive MAP kinase pathway and extracellular signal-regulated protein kinase (ERK) kinases (MEKs)
- The activation of and binding to MEK3 by TAOK1 implicates TAOK1 in the regulation of the p38-containing stress-responsive MAP kinase pathway
- A microtubule affinity-regulating kinase, TAOK1 (also known as MARKK) is an important regulator of mitotic progression, required for both chromosome congression and checkpoint-induced anaphase delay
- TAOK1 is involved in various processes such as p38/MAPK14 stress-activated MAPK cascase, DNA damage response, and regulations of cytoskeleton stability
- It phosphorylates MAP2K3, MAP2K6, and MARK2
- TAOK1 acts as an activator of the p38/MAPK cascade by mediating phosphorylation and subsequent activation of the upsteam MAP2K3 and MAP2K6 kinases
- It is involved in G-protein couples receptor signaling to p38/MAPK14
- In response to DNA damage, TAOK1, is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade by phosphorylaton of MAP2K3 and MAP2K6
- In addition, it acts as a regulator of cytoskeleton stability and a regulator of apoptosis.