TRPA1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533089-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA533089 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
TRPA1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Trpa1
Gene Alias
Anktm1; ankyrin-like with transmembrane domains 1; ankyrin-like with transmembrane domains protein 1; FEPS; ion channel; drTRPA1; nompC; transformation-sensitive protein p120; transient receptor potential A1; transient receptor potential ankyrin 1a; transient receptor potential cation channel subfamily A member 1; transient receptor potential cation channel subfamily A member 1a; transient receptor potential cation channel, subfamily A, member 1a; transient receptor potential cation channel subfamily A member 1-like; transient receptor potential cation channel, subfamily A, member 1; transient receptor potential cation channel, subfamily A, member 1 L homeolog; transient receptor potential cation channel, subfamily A, member 1a; TRPA1; TRPA-1; trpa1.L; trpa1a; TRPA1b; XELAEV_18003616mg
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8989
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
O75762
Gene Symbols
Trpa1
Immunogen
Synthetic 18 amino acid peptide from internal region of human TRPA1.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (100%); Marmoset (94%); Dog, Bovine, Elephant (89%); Rat, Bat, Panda, Horse, Rabbit (83%)
- For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
- TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction
- TRPA1 is a transformation -associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons
- Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage
- It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation
- The structure of TRPA1 is highly related to both the protein ankyrin and transmembrane proteins
- The specific function of TRPA1 has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.