COMT Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533446-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA533446 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
COMT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Comt
Gene Alias
Catechol O-methyltransferase; catecholamine-O-methyltransferase; catechol-O-methyltransferase; catechol-O-methyltransferase 1; catechol-O-methyltransferase isoform; Comt; Comt1; D16Wsu103e; D330014B15Rik; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; OTTHUMP00000197749; OTTHUMP00000197750; testicular tissue protein Li 42
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1312
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P21964
Gene Symbols
Comt
Immunogen
Synthetic 19 amino acid peptide from internal region of human COMT.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla (100%) Orangutan, Gibbon, Rabbit (95%) Monkey, Marmoset, Horse (89%) Mouse, Rat, Hamster (84%)
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine
- This O-methylation results in one of the major degradative pathways of the catecholamine transmitters
- In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease
- COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT)
- The differences between S-COMT and MB-COMT reside within the N-termini
- Several transcript variants are formed through the use of alternative translation initiation sites and promoters.