PIPA533834

GRPR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533834-Each-of-1 In Stock ₹ 46,502.50

PIPA533834 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

GRPR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRPR

Gene Alias

BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100517439, 100758098, 14829, 24938, 2925, 491754

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P21729, P30550, P52500

Gene Symbols

GRPR

Immunogen

Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human GRPR.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Canine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bovine, Dog, Bat, Pig (100%)
  • Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues
  • The effects of GRP are mediated through the gastrin-releasing peptide receptor
  • This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway
  • The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate
  • An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.