PIPA534408

ZFYVE21 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534408-Each-of-1 In Stock ₹ 47,392.50

PIPA534408 - Each of 1

₹ 47,392.50

In Stock

Quantity

1

Base Price: ₹ 47,392.50

GST (18%): ₹ 8,530.65

Total Price: ₹ 55,923.15

Antigen

ZFYVE21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ZFYVE21

Gene Alias

1110013H04Rik; AW558780; C85416; FYVE domain containing 21; HCV p7-transactivated protein 1; HCVP7TP1; ZF21; Zfyve21; Zinc finger FYVE domain-containing protein 21; zinc finger FYVE-type containing 21; zinc finger, FYVE domain containing 21

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

362789, 68520, 79038

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

D3ZVP7, Q8VCM3, Q9BQ24

Gene Symbols

ZFYVE21

Immunogen

A 15 amino acid synthetic peptide near the amino terminus of human ZF21

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is NIH-3T3 cell lysate
  • PA5-34408 can be used with blocking peptide PEP-1450
  • ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease
  • ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement
  • Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly
  • ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.