PIPA538897

COX11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538897-Each-of-1 In Stock ₹ 44,411.00

PIPA538897 - Each of 1

₹ 44,411.00

In Stock

Quantity

1

Base Price: ₹ 44,411.00

GST (18%): ₹ 7,993.98

Total Price: ₹ 52,404.98

Antigen

COX11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

COX11

Gene Symbols

COX11

Immunogen

A synthetic peptide derived from the internal region of human COX11

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9Y6N1, Q6P8I6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1353, 69802

Content And Storage

-20°C

Form

Liquid

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Description

  • Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen
  • This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes
  • The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex
  • This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies
  • However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX
  • This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane
  • Multiple transcript variants encoding different isoforms have been found for this gene
  • A related pseudogene has been found on chromosome 6
  • [provided by RefSeq, Jun 2009].