PIPA539019
MINT3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA539019-Each-of-1 | In Stock | ₹ 44,411.00 |
PIPA539019 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,411.00
GST (18%): ₹ 7,993.98
Total Price: ₹ 52,404.98
Antigen
MINT3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APBA3
Gene Alias
X11 like 2 protein 2, X11gamma, X11L2, APBA3, lin 10, MGC:15815, Mint 3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9546
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O96018
Gene Symbols
APBA3
Immunogen
A synthetic peptide derived from the internal region of human APBA3
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Amyloid beta precursor protein ( beta APP) is a major constituent of the amyloid deposits in patients with Alzheimer′s disease
- The amyloid beta precursor is known to interact with several proteins, including the G heterotrimetric protein, APP-BP1, and X11
- The neuronal, transmembrane protein X11 is known to bind to the amyloid beta precurser protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular beta APP and slowing beta APP processing pathways
- X11 binds specifically to the YENPTY motif, which is involved in the internalization of beta APP
- Multiple splice varitents of X11 have been identified, including X11 alpha, beta and gamma (also known as Mint 1, 2 and 3, respectively).