ATG2B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA551576-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA551576 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
ATG2B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATG2B
Gene Alias
2410024A21Rik; AI047755; AI503411; ATG2 autophagy related 2 homolog B; Atg2b; autophagy related 2B; autophagy-related protein 2 homolog B; AW558123; C030004M05Rik; C14orf103; C630028L02Rik; mKIAA4067; RGD1304878
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55102
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q96BY7
Gene Symbols
ATG2B
Immunogen
Recombinant protein corresponding to Human ATG2B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: CSKEMPRKAH SNMLTVKALH VCPESGRSPQ ECCLRVSLMP LRLNIDQDAL FFLKDFFTSL SAEVELQMTP DPEVKKSPGA DVTCSLPRHL STSKEPNLVI SFSGPKQPSQ NDSANSVEVV NGMEEKNFSA EEASFRDQPV Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 86%
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
- It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
- This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1
- Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets
- Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.