MAP4K2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA552422-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA552422 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
MAP4K2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP4K2
Gene Alias
AI385662; B lymphocyte serine/threonine protein kinase; B lymphocyte serine/threonine-protein kinase; BL44; dZ150L22.2; GC kinase; GCK; germinal center kinase; germinal centre kinase (GC kinase); LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 2; MAP4K2; map4k2l; map4k2l-2; map4k3l; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; mitogen activated protein kinase kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase kinase 2-like; mitogen-activated protein kinase kinase kinase kinase 3-like; Rab8 interacting protein; rab8-interacting protein; Rab8ip; si:dz150l22.2; si:dz263j20.1; Unknown (protein for MGC:136670); zgc:136670
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5871
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q12851
Gene Symbols
MAP4K2
Immunogen
Recombinant protein corresponding to Human MAP4K2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: ETDPLNEPWE EEWTLLGKEE LSGSLLQSVQ EALEERSLTI RSASEFQELD SPDDTMGTIK RAPFLGPLPT DPPAEEPLSS PPGTLPPPPS GPNSSPLLPT AWATMKQRE Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%
- MAP4K2 (GCK) is a serine/ threonine protein kinase that activates the JNK pathway
- Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of the germinal center, where it may participate in B-cell differentiation
- The kinase may also play a role in the regulation of vesicle targeting or fusion
- The protein encoded by MAP4K2 is a member of the serine/threonine protein kinase family
- Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation
- This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases
- This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.