cGKII Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA552426-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA552426 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
cGKII
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PRKG2
Gene Alias
AW212535; cGK 2; cGK2; cGKII; cGK-II; cGMP dependent protein kinase type II; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; EC 2.7.11.12; GDPKII; PRKG2; PRKGR2; protein kinase cGMP- dependent type 2; protein kinase, cGMP- dependent, type 2; protein kinase, cGMP- dependent, type II; protein kinase, cGMP-dependent, type II; testicular tissue protein Li 99; type II cGMP-dependent protein kinase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5593
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q13237
Gene Symbols
PRKG2
Immunogen
Recombinant protein corresponding to Human cGKII
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: REYHLKELRE QLSKQTVAIA ELTEELQNKC IQLNKLQDVV HMQGGSPLQA SPDKVPLEVH RKTSGLVSLH SRRGAKAGVS AEPTTRTYDL NKPPEFSFEK ARVRKDSSEK KLITDALNKN QFLKRLDPQQ IKDMVE Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%
- PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity
- cGKII is thought to play a key role in a diverse set of physiological pathway
- cGKII may mediate intestinal secretion of water and electrolytes induced by the E
- coli toxin STa and the intestinal peptide guanylin
- Identification of the pathway that mediates intestinal fluid secretion by E
- coli
- cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.