ST3GAL6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA553845-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA553845 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
ST3GAL6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ST3GAL6
Gene Alias
1700023B24Rik; AI930218; alpha2,3-sialyltransferase ST3Gal VI; alpha-2,3-sialyltransferase VI; AW552396; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; sia10; Sialyltransferase 10; sialyltransferase 10 (alpha-2,3-sialyltransferase VI); SIAT10; ST3 beta-galactoside alpha-2,3-sialyltransferase 6; ST3Gal VI; ST3GAL6; ST3GalVI; type 2 lactosamine alpha-2,3-sialyltransferase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10402
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
Lot-Specific
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9Y274
Gene Symbols
ST3GAL6
Immunogen
Recombinant protein corresponding to Human ST3GAL6
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: IQPCLSKPAF ASLLRFHQFH PFLCAADFRK IASLYGSDKF DLPYGMRTSA EYFRLALSKL QSCDLFDEFD NIPCKKCVVV GNGGVLKNKT LGEKIDSYDV IIRMNNG Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 75%
- Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups
- Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types
- However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness
- In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer
- At least three isoforms of ST3gal6 are known to exist.