PIPA553909

RBM28 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA553909-Each-of-1 In Stock ₹ 52,332.00

PIPA553909 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

RBM28

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rbm28

Gene Alias

2810480G15Rik; AI503051; ANES; hypothetical protein MGC56258; RBM28; RNA binding motif protein 28; RNA-binding motif protein 28; RNA-binding protein 28; zgc:56258

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55131

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NW13

Gene Symbols

Rbm28

Immunogen

Recombinant protein corresponding to Human RBM28

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RKLLLSATSG EKGVRIKECR VMRDLKGVHG NMKGQSLGYA FAEFQEHEHA LKALRLINNN PEIFGPLKRP IVEFSLEDRR KLKMKELRIQ RSLQKMRSKP ATGEPQKGQP EPAKDQQQK Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%
  • Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes
  • Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments
  • The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface
  • With VAPA, may regulate ER morphology
  • Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion
  • Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3
  • Also binds 25-hydroxycholesterol and cholesterol.