NUP88 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA554518-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA554518 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
NUP88
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NUP88
Gene Alias
88 kDa nuclear pore complex protein; 88 kDa nucleoporin; karyoporin; nuclear pore complex protein 88; nuclear pore complex protein Nup88; nucleoporin 88; nucleoporin 88kDa; nucleoporin Nup84; Nucleoporin Nup88; Nup84; NUP88; Prei2; preimplantation protein 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4927
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q99567
Gene Symbols
NUP88
Immunogen
Recombinant protein corresponding to Human NUP88
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: QLLTRNVVFG LGGELFLWDG EDSSFLVVRL RGPSGGGEEP ALSQYQRLLC INPPLFEIYQ VLLSPTQHHV ALIGIKGLMV LELPKRWGKN SEFEGGKSTV NCSTTPVAER FFTSSTSLTL KHAAWYPSEI LDPHVV Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%
- The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits
- Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG)
- Nup88 (nucleoporin 88 kDa) is a 741 amino acid protein that localizes to the nucleus and functions as an essential component of the nuclear pore complex
- Expressed ubiquitously, Nup88 is subject to phosphorylation by ATM or ATR and is upregulated in malignant neoplasms and precancerous dysplasias, suggesting a role in tumorigenesis
- The gene encoding Nup88 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes.