PIPA555400

SPACA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA555400-Each-of-1 In Stock ₹ 53,400.00

PIPA555400 - Each of 1

₹ 53,400.00

In Stock

Quantity

1

Base Price: ₹ 53,400.00

GST (18%): ₹ 9,612.00

Total Price: ₹ 63,012.00

Antigen

SPACA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPACA1

Gene Alias

1700124L11Rik; 4930540L03Rik; RGD1560284; SAMP32; SPACA1; Sperm acrosomal membrane-associated protein 32; sperm acrosome associated 1; sperm acrosome membrane-associated protein 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

81833

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9HBV2

Gene Symbols

SPACA1

Immunogen

Recombinant protein corresponding to Human SPACA1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: REVILTNGCP GGESKCVVRV EECRGPTDCG WGKPISESLE SVRLACIHTS PLNRFKYMWK L Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 89%
  • The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization
  • Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens
  • The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males
  • Furthermore, antibodies generated against the recombinant protein block in vitro fertilization
  • This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.