PIPA556679

BYSL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA556679-Each-of-1 In Stock ₹ 49,439.50

PIPA556679 - Each of 1

₹ 49,439.50

In Stock

Quantity

1

Base Price: ₹ 49,439.50

GST (18%): ₹ 8,899.11

Total Price: ₹ 58,338.61

Antigen

BYSL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BYSL

Gene Alias

by the ribosomal protein s6 gene, drosophila, homolog-like; Bys; BYSL; bysl {ECO:0000312; Bystin; bystin like; bystin-like; EMBL:AAH79030.1, ECO:0000312; Enp1; RGD:727959}

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

53414, 705

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O54825, Q13895

Gene Symbols

BYSL

Immunogen

Recombinant protein corresponding to Human BYSL

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LDALVFHFLG FRTEKRELPV LWHQCLLTLV QRYKADLATD QKEALLELLR LQPHPQLSPE IRRELQSAVP RDVEDVPITV E Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%
  • Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells
  • Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present
  • Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation
  • Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy
  • Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface
  • After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.