PIPA557592

CaBP8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA557592-Each-of-1 In Stock ₹ 48,905.50

PIPA557592 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

CaBP8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CALN1

Gene Alias

9630012C17Rik; CABP8; calcium-binding protein 8; calcium-binding protein CABP8; CALN1; calneuron 1; calneuron I; Calneuron-1; calneuron-I; MNCb-0849

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

83698

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9BXU9

Gene Symbols

CALN1

Immunogen

Recombinant protein corresponding to Human CaBP8

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: FDEFMTILGP KLVSSEGRDG FLGNTIDSIF WQFDMQRITL EELKHILYHA FRDHLTMKDI E Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%
  • Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system
  • The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I
  • CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I
  • It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity
  • Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.