PIPA558063

SHROOM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA558063-Each-of-1 In Stock ₹ 48,905.50

PIPA558063 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

SHROOM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SHROOM1

Gene Alias

apical protein 2; Apx; APXL2; KIAA1960; Protein Shroom1; RGD1308066; Shrm1; Shroom; shroom family member 1; Shroom1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

134549

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q2M3G4

Gene Symbols

SHROOM1

Immunogen

Recombinant protein corresponding to Human SHROOM1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VREVLVRALP VEELRVYCAL LAGKAAVLAQ QRNLDERIRL LQDQLDAIRD DLGHHAPSPS PARPPGTCPP VQPPFPLLLT Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 51%
  • SHROOM family members play diverse roles in the development of the nervous system and other tissues
  • SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis
  • It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium
  • SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.