SUPV3L1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA558380-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA558380 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
SUPV3L1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SUPV3L1
Gene Alias
6330443E10Rik; ATP-dependent RNA helicase SUPV3L1, mitochondrial; Suppressor of var1 3-like protein 1; suppressor of var1, 3-like 1; suppressor of var1, 3-like 1 (S. cerevisiae); suppressor of var1, 3-like 1(SUV3); SUPV3L1; SUV3; Suv3 like RNA helicase; Suv3l1; SUV3-like helicase; SUV3-like protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6832
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8IYB8
Gene Symbols
SUPV3L1
Immunogen
Recombinant protein corresponding to Human SUPV3L1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: IQHIPLSLRV RYVFCTAPIN KKQPFVCSSL LQFARQYSRN EPLTFAWLRR YIKWPLLPPK NIKDLMDLEA VH Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%
- Major helicase player in mitochondrial RNA metabolism
- Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner
- Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (PubMed:29967381)
- ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction
- Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates
- Also implicated in recombination and chromatin maintenance pathways
- May protect cells from apoptosis
- Associates with mitochondrial DNA
- [UniProt]